When more encouraging was dropped and the pyorrhea pockets became heavier, the overall conditions and outlook changed remarkably. The surprise was that the amount of systemic body changes found to happen. Among them were the appreciable quantity of absorption of bone; the incidence or non-occurrence of dental caries (cavities); changes in the uric acid level; and, furthermore, changes in the blood and saliva of the ionic calcium level, and its urea nitrogen content.

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It also became apparent that the presence or lack of gum infections was directly linked to the patient’s calcium metabolism. When the ionic amount of calcium in the blood was greater than normal, the gum and bone tended to be consumed away more readily in the presence of . At exactly the exact same time, studies of saliva demonstrated it to be more alkaline than normal when was active. Another huge surprise happened when the contents of the pus pockets were found to be quite alkaline, having a as high as 7.7, when dentists would presume it be acid.

One would think that if teeth affected by periodontal disease are extracted there are some difficulties with recovery. Quite the contrary, sockets developed great blood clots and cured quickly, without the development of a sterile socket.On the other hand, those cases marked by the formation of the dense bone of condensing osteitis beneath the tooth’s root conclusion proved to be painful, treated slowly, they developed blood clots that easily broke down, and lots of these cases developed the dreaded dry socket.

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An analysis of the saliva of these patients revealed it to be reduced in alkalinity and the blood lower in ionic calcium. It should be apparent now that the instances mentioned involve two different kinds of individuals. This was carried out even more dramatically when two unique kinds of extraction sockets were analyzed under a microscope. Here, also, the disparity proved so certain as to be of diagnostic value. The Sockets of teeth extracted due to pyorrhea were found to comprise primarily polymorphonuclear white blood cells using several lobes.

Many granules (granulocytes) were seen under the microscope and these cells showed rapid movements. The white cells have been seen to do their work of engulfing the germs, and just some of those organisms escaped entrapment. Sockets of teeth extracted for root end infections when condensing osteitis was present had just a few white blood cells(leucocytes) and granules,but massive numbers of organisms out these cells.


These research efforts demonstrated that as alkalinity went down,ionic calcium level went up. Such instances were accompanied by acute inflammatory responses to irritation brokers with degradation of gum attachments and absorption of alveolar bone. Dentists appeared upon pyorrhea as being primarily an infectious disease at the time of the Price studies, and many still do today. You can see from the data which, although bacteria are found, pyorrhea isn’t because of a certain infection but, instead, entails certain systemic body ailments. The factors have been found to be associated with a individual’s particular susceptibility and biological inheritance; that is, they are connected in a really difinite means to your own biological defense and ability of their .